St. James of the Marches was a Franciscan priest in the 15th century. He was born into a poor family in Monteprandone, Italy in 1391 and was educated by his uncle who was a priest. He continued his education, eventually achieving the degree of Doctor in Canon and Civil Law from the University of Perugia. He worked for some time as a tutor in a noble family, but on July 26, 1416, he was received into the order of Friars Minor in the Chapel of the Portiuncula in Assisi.After completing his novitiate, he studied theology under St. Bernardine of Siena. On June 13, 1420, St. James was ordained a priest, and soon began to preach in Tuscany, in the Marches, and in Umbria. For half a century, he continued as a missionary and preacher. St James of the Marches preached penance, combated heretics, and was on legations in Germany, Austria, Sweden, Denmark, Bohemia, Poland, Hungary, and Bosnia. He was also appointed inquisitor against the Fratelli, a heretic sect that dissented from the Franciscans on the vow of poverty, among other things. He was offered the See of Milan in 1460, but he refused it. Inspired by St. Jame's apostolic example, more than 200 young men of Germany were impelled to enter the Franciscan Order. The crowds who came to hear him were so great that the churches were not large enough to accommodate them, and it became imperative for him to preach in the public squares. At Milan he was instrumental in converting 36 women of bad repute by a single sermon on St. Mary Magdalen. It is said that he brought 50,000 heretics into the Church and led 200,000 nonbelievers to baptism. In addition, God granted St James such wisdom that popes and princes sought counsel from him. He possessed the gifts or miracles and of prophesy in great measure, yet his humility surpassed all those distinctions. On Easter Monday, 1462, St. James, while preaching at Brescia, repeated the ideas of some theologians that the Precious Blood shed during the Passion was not united with the Divinity of Christ during the three days of His burial. He was accused of heresy for saying that, but no discussion or resolution was ever granted to his case, and the matter was ignored or forgotten. James spent the last three years of his life at Naples, and was buried there in the Franciscan church of St. Maria la Nuova, where his body can be seen today.He was beatified by Urban VIII in 1624 and was canonized by Benedict XIII in 1726. Naples venerates him as one of its patron saints.

On November 28, the Church honors St. Catherine Labouré, the humble Daughter of Charity to whom Mary appeared, requesting that the Miraculous Medal be stamped so that all who wear it would receive great graces. Saint Catherine Labouré was born in France on May 2, 1806. She was the ninth of 11 children. Upon her mother’s death, when Catherine was eight years old, the young girl assumed the responsibilities of the household. It was said of her that she was a very quiet and practical child. Eventually she became a Daughter of Charity, and when she was still a novice at the age of 24, the Virgin Mary appeared to her for the first time. Later, Mary appeared once again and requested that Catherine have a medal made portraying Mary just as she appeared. It took two years before Catherine was able to convince her spiritual director to have the medal created, but eventually, he listened to her and 2,000 medals were made. Their dispersal was so rapid and effective that it was said to be miraculous itself. After the visions ceased, St. Catherine Labouré spent the rest of her life in humble and obedient service as the portress, and worked with the sick in a convent outside of Paris. She spent that time in silence, not telling her superior that she was the one to whom Mary appeared and gave the medal until 45 years after.She died in Paris on December 31, 1876 and was canonized in 1947 by Pope Pius XII. Her incorrupt body lies in the crypt of the convent.